8BF1
High-resolution structure of unliganded PPAR gamma in complex with the peptide PGC-1 alpha
Summary for 8BF1
| Entry DOI | 10.2210/pdb8bf1/pdb |
| Descriptor | Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (3 entities in total) |
| Functional Keywords | ppar gamma activation, co-activator peptide, ligand binding domain, nuclear receptor, nuclear protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 34479.96 |
| Authors | Useini, A.,Straeter, N. (deposition date: 2022-10-23, release date: 2023-03-08, Last modification date: 2024-02-07) |
| Primary citation | Useini, A.,Engelberger, F.,Kunze, G.,Strater, N. Structural basis of the activation of PPAR gamma by the plasticizer metabolites MEHP and MINCH. Environ Int, 173:107822-107822, 2023 Cited by PubMed: 36841188DOI: 10.1016/j.envint.2023.107822 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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