8BF1

High-resolution structure of unliganded PPAR gamma in complex with the peptide PGC-1 alpha

8BF1 の概要

• エントリーDOI: 10.2210/pdb8bf1/pdb
• 分子名称: Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (3 entities in total)
• 機能のキーワード: ppar gamma activation, co-activator peptide, ligand binding domain, nuclear receptor, nuclear protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34479.96

構造登録者

Useini, A.,Straeter, N. (登録日: 2022-10-23, 公開日: 2023-03-08, 最終更新日: 2024-02-07)

• 主引用文献: Useini, A.,Engelberger, F.,Kunze, G.,Strater, N.; Structural basis of the activation of PPAR gamma by the plasticizer metabolites MEHP and MINCH.; Environ Int, 173:107822-107822, 2023; PubMed: 36841188; DOI: 10.1016/j.envint.2023.107822

実験手法

X-RAY DIFFRACTION (1.36 Å)