8BCT
X-ray crystal structure of a de novo selected helix-loop-helix heterodimer in a syn arrangement, 26alpha/26beta
Summary for 8BCT
Entry DOI | 10.2210/pdb8bct/pdb |
Descriptor | 26alpha, 26beta, SULFATE ION, ... (6 entities in total) |
Functional Keywords | coiled coil, 4-helix bundle, in-cell library screening, protein-protein interactions, de novo protein |
Biological source | synthetic construct More |
Total number of polymer chains | 8 |
Total formula weight | 43534.53 |
Authors | Naudin, E.A.,Mylemans, B.,Smith, A.J.,Savery, N.J.,Woolfson, D.N. (deposition date: 2022-10-17, release date: 2023-06-07, Last modification date: 2024-05-01) |
Primary citation | Smith, A.J.,Naudin, E.A.,Edgell, C.L.,Baker, E.G.,Mylemans, B.,FitzPatrick, L.,Herman, A.,Rice, H.M.,Andrews, D.M.,Tigue, N.,Woolfson, D.N.,Savery, N.J. Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology. Acs Synth Biol, 12:1845-1858, 2023 Cited by PubMed: 37224449DOI: 10.1021/acssynbio.3c00231 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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