8BCT

X-ray crystal structure of a de novo selected helix-loop-helix heterodimer in a syn arrangement, 26alpha/26beta

8BCT の概要

• エントリーDOI: 10.2210/pdb8bct/pdb
• 分子名称: 26alpha, 26beta, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: coiled coil, 4-helix bundle, in-cell library screening, protein-protein interactions, de novo protein
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 43534.53

構造登録者

Naudin, E.A.,Mylemans, B.,Smith, A.J.,Savery, N.J.,Woolfson, D.N. (登録日: 2022-10-17, 公開日: 2023-06-07, 最終更新日: 2024-05-01)

• 主引用文献: Smith, A.J.,Naudin, E.A.,Edgell, C.L.,Baker, E.G.,Mylemans, B.,FitzPatrick, L.,Herman, A.,Rice, H.M.,Andrews, D.M.,Tigue, N.,Woolfson, D.N.,Savery, N.J.; Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology.; Acs Synth Biol, 12:1845-1858, 2023; PubMed: 37224449; DOI: 10.1021/acssynbio.3c00231

実験手法

X-RAY DIFFRACTION (1.7 Å)