8B96
Crystal structure of the human BRD4-BD1 bromodomain in complex with the inhibitor CRCM5464
8B96 の概要
エントリーDOI | 10.2210/pdb8b96/pdb |
分子名称 | Bromodomain-containing protein 4, ~{N}-[[4-[[7-ethyl-2,6-bis(oxidanylidene)purin-3-yl]methyl]cyclohexyl]methyl]-3-fluoranyl-4-(oxan-4-yloxy)benzenesulfonamide, 1,2-ETHANEDIOL, ... (5 entities in total) |
機能のキーワード | epigenetic, inhibition, inhibitor, selectivity, complex, bd1, protein binding |
由来する生物種 | Homo sapiens (human) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 15865.29 |
構造登録者 | |
主引用文献 | Carrasco, K.,Betzi, S.,Morelli, X. Crystal structure of the human BRD4-BD1 bromodomain in complex with the inhibitor CRCM5464 To Be Published, |
実験手法 | X-RAY DIFFRACTION (1.338 Å) |
構造検証レポート
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