8B76

The crystal structure of M644G variant of DNA Pol Epsilon containing dTTP in the polymerase active site

Summary for 8B76

Entry DOI	10.2210/pdb8b76/pdb
Related	8b67 8b6k
Descriptor	DNA polymerase epsilon catalytic subunit A, Primer DNA sequence, Template DNA sequence, ... (7 entities in total)
Functional Keywords	protein-dna complex, dna binding protein
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Total number of polymer chains	6
Total formula weight	291908.53
Authors	Parkash, V.,Johansson, E. (deposition date: 2022-09-28, release date: 2023-11-01)
Primary citation	Parkash, V.,Kulkarni, Y.,Bylund, G.O.,Osterman, P.,Kamerlin, S.C.L.,Johansson, E. A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023 Cited by PubMed: 37819038 DOI: 10.1093/nar/gkad817 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation