8B04

STRUCTURE OF PORCINE PANCREATIC ELASTASE BOUND TO A FRAGMENT OF AN ISOXAZOLONE INHIBITOR

Summary for 8B04

• Entry DOI: 10.2210/pdb8b04/pdb
• Descriptor: Chymotrypsin-like elastase family member 1, DIMETHYL SULFOXIDE, 2-cyclopropylcarbonyl-3-propan-2-yl-1,2-oxazol-5-one, ... (5 entities in total)
• Functional Keywords: chymotrypsin family, serine protease, lyase
• Biological source: Sus scrofa (pig)
• Total number of polymer chains: 1
• Total formula weight: 29236.96

Authors

Ferraroni, M.,Giovannoni, P.,Masini, V. (deposition date: 2022-09-07, release date: 2023-09-20)

• Primary citation: Gerace, A.,Masini, V.,Crocetti, L.,Giovannoni, M.P.,Ferraroni, M.; X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones; J.Mol.Struct., 1274:134595-, 2023; DOI: 10.1016/j.molstruc.2022.134595

Experimental method

X-RAY DIFFRACTION (1.6 Å)