8AXZ

Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with S-adenosylmethionine, adenosin and diphosphono-aminophosphonic acid.

Summary for 8AXZ

• Entry DOI: 10.2210/pdb8axz/pdb
• Descriptor: S-adenosylmethionine synthase isoform type-2, (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, ... (9 entities in total)
• Functional Keywords: methionine adenosyltransferase, sam-producing metabolic enzyme, cancer target, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 45169.47

Authors

Nawrotek, A.,Vuillard, L.,Miallau, L. (deposition date: 2022-09-01, release date: 2022-10-05, Last modification date: 2024-01-31)

• Primary citation: Nawrotek, A.,Vuillard, L.,Miallau, L.; Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with S-adenosylmethionine, adenosin and diphosphono-aminophosphonic acid.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.154 Å)