8AXZ

Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with S-adenosylmethionine, adenosin and diphosphono-aminophosphonic acid.

8AXZ の概要

• エントリーDOI: 10.2210/pdb8axz/pdb
• 分子名称: S-adenosylmethionine synthase isoform type-2, (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, ... (9 entities in total)
• 機能のキーワード: methionine adenosyltransferase, sam-producing metabolic enzyme, cancer target, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45169.47

構造登録者

Nawrotek, A.,Vuillard, L.,Miallau, L. (登録日: 2022-09-01, 公開日: 2022-10-05, 最終更新日: 2024-01-31)

• 主引用文献: Nawrotek, A.,Vuillard, L.,Miallau, L.; Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with S-adenosylmethionine, adenosin and diphosphono-aminophosphonic acid.; To Be Published,

実験手法

X-RAY DIFFRACTION (1.154 Å)