8AUI

Xenobiotic reductase A Y27F variant in complex with 2-methoxyethyl (Z)-2-(hydroxyimino)-3-oxobutanoate

Summary for 8AUI

Entry DOI	10.2210/pdb8aui/pdb
Descriptor	NADH:flavin oxidoreductase, FLAVIN MONONUCLEOTIDE, 2-methoxyethyl (2~{Z})-2-hydroxyimino-3-oxidanylidene-butanoate, ... (5 entities in total)
Functional Keywords	ene-reductase, fmn, oxime, tim-barrel, oxidoreductase
Biological source	Pseudomonas putida
Total number of polymer chains	2
Total formula weight	84132.01
Authors	Polidori, N.,Gruber, K. (deposition date: 2022-08-25, release date: 2023-03-01, Last modification date: 2024-02-07)
Primary citation	Breukelaar, W.B.,Polidori, N.,Singh, A.,Daniel, B.,Glueck, S.M.,Gruber, K.,Kroutil, W. Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines. Acs Catalysis, 13:2610-2618, 2023 Cited by PubMed: 36846821 DOI: 10.1021/acscatal.2c06137 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation