8AN9
Fucosylated mixed-chirality linear peptide FHP5 bound to the fucose binding lectin LecB PA-IIL from Pseudomonas aeruginosa at 1.3 Angstrom resolution.
This is a non-PDB format compatible entry.
Summary for 8AN9
| Entry DOI | 10.2210/pdb8an9/pdb |
| Descriptor | Fucose-binding lectin PA-IIL, Mixed-chirality peptide FHP5, CALCIUM ION, ... (5 entities in total) |
| Functional Keywords | antimicrobial peptide, alpha helix, mixed-chirality, antibiotic |
| Biological source | Pseudomonas aeruginosa PAO1 More |
| Total number of polymer chains | 7 |
| Total formula weight | 52055.74 |
| Authors | Personne, H.,Stocker, A.,Reymond, J.-L. (deposition date: 2022-08-04, release date: 2023-05-31, Last modification date: 2024-02-07) |
| Primary citation | Personne, H.,Paschoud, T.,Fulgencio, S.,Baeriswyl, S.,Kohler, T.,van Delden, C.,Stocker, A.,Javor, S.,Reymond, J.L. To Fold or Not to Fold: Diastereomeric Optimization of an alpha-Helical Antimicrobial Peptide. J.Med.Chem., 66:7570-7583, 2023 Cited by PubMed: 37227046DOI: 10.1021/acs.jmedchem.3c00460 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.273 Å) |
Structure validation
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