8AN5

MenAT1 toxin-antitoxin complex (rv0078a-rv0078b) from Mycobacterium tuberculosis H37Rv

Summary for 8AN5

• Entry DOI: 10.2210/pdb8an5/pdb
• Related: 8AN4
• Descriptor: Bacterial toxin, Conserved protein (3 entities in total)
• Functional Keywords: toxin-antitoxin tuberculosis nucleotidyltransferase ment menat, toxin
• Biological source: Mycobacterium tuberculosis H37Rv; More
• Total number of polymer chains: 3
• Total formula weight: 50435.09

Authors

Xu, X.,Usher, B.,Gutierrez, C.,Barriot, R.,Arrowsmith, T.J.,Han, X.,Redder, P.,Neyrolles, O.,Blower, T.R.,Genevaux, P. (deposition date: 2022-08-04, release date: 2023-08-02, Last modification date: 2023-08-30)

• Primary citation: Xu, X.,Usher, B.,Gutierrez, C.,Barriot, R.,Arrowsmith, T.J.,Han, X.,Redder, P.,Neyrolles, O.,Blower, T.R.,Genevaux, P.; MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding.; Nat Commun, 14:4644-4644, 2023; PubMed: 37591829; DOI: 10.1038/s41467-023-40264-3

Experimental method

X-RAY DIFFRACTION (1.44 Å)