8AIY
STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PAO1 IN COMPLEX WITH N-(beta-L-Fucopyranosyl)-biphenyl-3-carboxamide (4i)
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Summary for 8AIY
Entry DOI | 10.2210/pdb8aiy/pdb |
Descriptor | Fucose-binding lectin PA-IIL, CALCIUM ION, N-(beta-L-Fucopyranosyl)-biphenyl-3-carboxamide, ... (5 entities in total) |
Functional Keywords | p. aeruginosa lectin, lecb, inhibitor, sugar binding protein |
Biological source | Pseudomonas aeruginosa PAO1 |
Total number of polymer chains | 4 |
Total formula weight | 48825.07 |
Authors | Meiers, J.,Mala, P.,Varrot, A.,Siebs, E.,Imberty, A.,Titz, A. (deposition date: 2022-07-27, release date: 2022-11-02, Last modification date: 2024-01-31) |
Primary citation | Mala, P.,Siebs, E.,Meiers, J.,Rox, K.,Varrot, A.,Imberty, A.,Titz, A. Discovery of N -beta-l-Fucosyl Amides as High-Affinity Ligands for the Pseudomonas aeruginosa Lectin LecB. J.Med.Chem., 65:14180-14200, 2022 Cited by PubMed: 36256875DOI: 10.1021/acs.jmedchem.2c01373 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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