8A5Z

Imine Reductase from Ensifer adhaerens A208N mutant in complex with NADP+

Summary for 8A5Z

• Entry DOI: 10.2210/pdb8a5z/pdb
• Related: 8A3X
• Descriptor: NAD_binding_2 domain-containing protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, IODIDE ION, ... (4 entities in total)
• Functional Keywords: amine, nadp, imine reductase oxidoreductase, oxidoreductase
• Biological source: Ensifer adhaerens
• Total number of polymer chains: 2
• Total formula weight: 64798.53

Authors

Gilio, A.K.,Grogan, G. (deposition date: 2022-06-16, release date: 2023-03-08, Last modification date: 2024-02-07)

• Primary citation: Gilio, A.K.,Thorpe, T.W.,Heyam, A.,Petchey, M.R.,Pogranyi, B.,France, S.P.,Howard, R.M.,Karmilowicz, M.J.,Lewis, R.,Turner, N.,Grogan, G.; A Reductive Aminase Switches to Imine Reductase Mode for a Bulky Amine Substrate.; Acs Catalysis, 13:1669-1677, 2023; PubMed: 36776386; DOI: 10.1021/acscatal.2c06066

Experimental method

X-RAY DIFFRACTION (2.31 Å)