8A3X

Imine Reductase from Ensifer adhaerens in complex with NADP+

Summary for 8A3X

Entry DOI	10.2210/pdb8a3x/pdb
Descriptor	NAD_binding_2 domain-containing protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... (4 entities in total)
Functional Keywords	imine reductase, ired, nadp+, oxidoreductase, amine
Biological source	Ensifer adhaerens
Total number of polymer chains	4
Total formula weight	127550.89
Authors	Gilio, A.K.,Grogan, G. (deposition date: 2022-06-09, release date: 2023-03-08, Last modification date: 2024-02-07)
Primary citation	Gilio, A.K.,Thorpe, T.W.,Heyam, A.,Petchey, M.R.,Pogranyi, B.,France, S.P.,Howard, R.M.,Karmilowicz, M.J.,Lewis, R.,Turner, N.,Grogan, G. A Reductive Aminase Switches to Imine Reductase Mode for a Bulky Amine Substrate. Acs Catalysis, 13:1669-1677, 2023 Cited by PubMed: 36776386 DOI: 10.1021/acscatal.2c06066 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.58 Å)

Structure validation