8A3I

X-ray crystal structure of a de novo designed antiparallel coiled-coil homotetramer with 3 heptad repeats, apCC-Tet*3

8A3I の概要

• エントリーDOI: 10.2210/pdb8a3i/pdb
• 分子名称: apCC-Tet*3 (2 entities in total)
• 機能のキーワード: coiled coil, 4-helix bundle, de novo protein design, peptide assembly, de novo protein
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 5298.19

構造登録者

Naudin, E.A.,Mylemans, B.,Albanese, K.I.,Woolfson, D.N. (登録日: 2022-06-08, 公開日: 2022-10-05, 最終更新日: 2024-05-01)

• 主引用文献: Naudin, E.A.,Albanese, K.I.,Smith, A.J.,Mylemans, B.,Baker, E.G.,Weiner, O.D.,Andrews, D.M.,Tigue, N.,Savery, N.J.,Woolfson, D.N.; From peptides to proteins: coiled-coil tetramers to single-chain 4-helix bundles.; Chem Sci, 13:11330-11340, 2022; PubMed: 36320580; DOI: 10.1039/d2sc04479j

実験手法

X-RAY DIFFRACTION (1.42 Å)