8A1Z

Crystal structure of Phosphoserine phosphatase SerB from Mycobacterium avium in complex with 1-(2,4-dichlorophenyl)-3-hydroxyurea

8A1Z の概要

• エントリーDOI: 10.2210/pdb8a1z/pdb
• 分子名称: Phosphoserine phosphatase, MAGNESIUM ION, 1-(2,4-dichlorophenyl)-3-oxidanyl-urea, ... (5 entities in total)
• 機能のキーワード: phosphoserine phosphatase, fragment, avium, hydrolase
• 由来する生物種: Mycobacterium avium 104
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44132.89

構造登録者

Haufroid, M.,Wouters, J. (登録日: 2022-06-02, 公開日: 2022-11-23, 最終更新日: 2024-01-31)

• 主引用文献: Haufroid, M.,Volkov, A.N.,Wouters, J.; Targeting the phosphoserine phosphatase MtSerB2 for tuberculosis drug discovery, an hybrid knowledge based /fragment based approach.; Eur.J.Med.Chem., 245:114935-114935, 2022; PubMed: 36403421; DOI: 10.1016/j.ejmech.2022.114935

実験手法

X-RAY DIFFRACTION (2.28 Å)