7ZYD

Structure of Compound 6 Bound to CK2alpha

7ZYD の概要

• エントリーDOI: 10.2210/pdb7zyd/pdb
• 分子名称: Casein kinase II subunit alpha, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: fragment based drug discovery, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39887.15

構造登録者

Brear, P.,Hyvonen, M. (登録日: 2022-05-24, 公開日: 2022-10-12, 最終更新日: 2024-01-31)

• 主引用文献: Brear, P.,De Fusco, C.,Atkinson, E.L.,Iegre, J.,Francis-Newton, N.J.,Venkitaraman, A.R.,Hyvonen, M.,Spring, D.R.; A fragment-based approach leading to the discovery of inhibitors of CK2 alpha with a novel mechanism of action.; Rsc Med Chem, 13:1420-1426, 2022; PubMed: 36426237; DOI: 10.1039/d2md00161f

実験手法

X-RAY DIFFRACTION (1.404 Å)