7ZXQ

cryo-EM structure of Connexin 32 R22G mutation hemi channel

Summary for 7ZXQ

Entry DOI	10.2210/pdb7zxq/pdb
EMDB information	15014
Descriptor	Gap junction beta-1 protein (1 entity in total)
Functional Keywords	connexin, gap junction channel, cell communication, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	6
Total formula weight	191792.36
Authors	Qi, C.,Korkhov, V.M. (deposition date: 2022-05-22, release date: 2023-05-31, Last modification date: 2024-06-05)
Primary citation	Qi, C.,Lavriha, P.,Bayraktar, E.,Vaithia, A.,Schuster, D.,Pannella, M.,Sala, V.,Picotti, P.,Bortolozzi, M.,Korkhov, V.M. Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels. Sci Adv, 9:eadh4890-eadh4890, 2023 Cited by PubMed: 37647412 DOI: 10.1126/sciadv.adh4890 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.53 Å)

Structure validation