7ZVK

Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-IMP)

Summary for 7ZVK

• Entry DOI: 10.2210/pdb7zvk/pdb
• Descriptor: Stimulator of interferon protein, 9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9-fluoranyl-3,12,18-tris(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]-3~{H}-purin-6-one (2 entities in total)
• Functional Keywords: sting, antiviral, activator, antiviral protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 47037.54

Authors

Klima, M.,Smola, M.,Boura, E. (deposition date: 2022-05-16, release date: 2023-11-29)

• Primary citation: Klima, M.,Smola, M.,Boura, E.; Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-IMP); To Be Published,

Experimental method

X-RAY DIFFRACTION (2.83 Å)