7ZV8
Crystal structure of SARS Cov-2 main protease in complex with an inhibitor 58
Summary for 7ZV8
Entry DOI | 10.2210/pdb7zv8/pdb |
Related PRD ID | PRD_002412 |
Descriptor | 3C-like proteinase nsp5, inhibitor 58, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | sars cov-2, 3cl, main protease, antiviral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 4 |
Total formula weight | 69253.36 |
Authors | Rahimova, R.,Di Micco, S.,Marquez, J.A. (deposition date: 2022-05-13, release date: 2022-12-07, Last modification date: 2024-02-07) |
Primary citation | Di Micco, S.,Rahimova, R.,Sala, M.,Scala, M.C.,Vivenzio, G.,Musella, S.,Andrei, G.,Remans, K.,Mammri, L.,Snoeck, R.,Bifulco, G.,Di Matteo, F.,Vestuto, V.,Campiglia, P.,Marquez, J.A.,Fasano, A. Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2. Eur.J.Med.Chem., 244:114857-114857, 2022 Cited by PubMed: 36332548DOI: 10.1016/j.ejmech.2022.114857 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.937 Å) |
Structure validation
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