7ZT5

Structure of E8 TCR in complex in human MR1 bound to 3FSA

Summary for 7ZT5

• Entry DOI: 10.2210/pdb7zt5/pdb
• Descriptor: Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, TCR alpha, ... (6 entities in total)
• Functional Keywords: mr1, tcr, 3-formylsalicylic acid, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 97956.03

Authors

Karuppiah, V.,Robinson, R.A. (deposition date: 2022-05-09, release date: 2023-06-28, Last modification date: 2024-02-07)

• Primary citation: Chancellor, A.,Alan Simmons, R.,Khanolkar, R.C.,Nosi, V.,Beshirova, A.,Berloffa, G.,Colombo, R.,Karuppiah, V.,Pentier, J.M.,Tubb, V.,Ghadbane, H.,Suckling, R.J.,Page, K.,Crean, R.M.,Vacchini, A.,De Gregorio, C.,Schaefer, V.,Constantin, D.,Gligoris, T.,Lloyd, A.,Hock, M.,Srikannathasan, V.,Robinson, R.A.,Besra, G.S.,van der Kamp, M.W.,Mori, L.,Calogero, R.,Cole, D.K.,De Libero, G.,Lepore, M.; Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.; J.Exp.Med., 220:-, 2023; PubMed: 37382893; DOI: 10.1084/jem.20221939

Experimental method

X-RAY DIFFRACTION (2.09 Å)