7ZSS

cryo-EM structure of D614 spike in complex with de novo designed binder

7ZSS の概要

• エントリーDOI: 10.2210/pdb7zss/pdb
• EMDBエントリー: 14930 14947
• 分子名称: Spike glycoprotein, de novo designed binder, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: sars-cov2, de novo, design binder, spike, rbd, receptor binding domain, antiviral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 416457.67

構造登録者

Pablo, G.,Sarah, W.,Alexandra, V.H.,Anthony, M.,Andreas, S.,Zander, H.,Dongchun, N.,Shuguang, T.,Freyr, S.,Casper, G.,Priscilla, T.,Alexandra, T.,Stephane, R.,Sandrine, G.,Jane, M.,Aaron, P.,Zepeng, X.,Yan, C.,Pu, H.,George, G.,Elisa, O.,Beat, F.,Didier, T.,Henning, S.,Michael, B.,Bruno, E.C. (登録日: 2022-05-08, 公開日: 2023-03-01, 最終更新日: 2023-05-24)

• 主引用文献: Gainza, P.,Wehrle, S.,Van Hall-Beauvais, A.,Marchand, A.,Scheck, A.,Harteveld, Z.,Buckley, S.,Ni, D.,Tan, S.,Sverrisson, F.,Goverde, C.,Turelli, P.,Raclot, C.,Teslenko, A.,Pacesa, M.,Rosset, S.,Georgeon, S.,Marsden, J.,Petruzzella, A.,Liu, K.,Xu, Z.,Chai, Y.,Han, P.,Gao, G.F.,Oricchio, E.,Fierz, B.,Trono, D.,Stahlberg, H.,Bronstein, M.,Correia, B.E.; De novo design of protein interactions with learned surface fingerprints.; Nature, 617:176-184, 2023; PubMed: 37100904; DOI: 10.1038/s41586-023-05993-x

実験手法

ELECTRON MICROSCOPY (2.63 Å)