7ZPY
Influenza polymerase A C-terminal domain of PA subunit with optimized small peptide inhibitor
Summary for 7ZPY
Entry DOI | 10.2210/pdb7zpy/pdb |
Descriptor | Polymerase acidic protein, Peptide inhibitor (ASP-TYR-ASN-PRO-TYR-LEU-LEU-TYR-LEU-LYS), METHOXY-ETHOXYL, ... (4 entities in total) |
Functional Keywords | antiviral peptides, influenza a polymerase, protein-protein interaction, viral protein |
Biological source | Influenza A virus (A/California/07/2009(H1N1)) More |
Total number of polymer chains | 2 |
Total formula weight | 54317.22 |
Authors | Radilova, K.,Brynda, J. (deposition date: 2022-04-29, release date: 2022-10-26, Last modification date: 2024-01-31) |
Primary citation | Radilova, K.,Zima, V.,Kral, M.,Machara, A.,Majer, P.,Hodek, J.,Weber, J.,Brynda, J.,Strmen, T.,Konvalinka, J.,Kozisek, M. Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction. Antiviral Res., 208:105449-105449, 2022 Cited by PubMed: 36265804DOI: 10.1016/j.antiviral.2022.105449 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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