7ZLK

AMC009 SOSIPv5.2 in complex with Fabs ACS101 and ACS124

7ZLK の概要

• エントリーDOI: 10.2210/pdb7zlk/pdb
• EMDBエントリー: 14783
• 分子名称: AMC009 SOSIPv5.2 envelope glycoprotein gp120, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• 機能のキーワード: hiv-1, antibodies, silent face, gp120-gp41 interface, viral protein
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 360729.83

構造登録者

van Schooten, J.,Ozorowski, G.,Ward, A. (登録日: 2022-04-15, 公開日: 2022-09-21, 最終更新日: 2022-11-30)

• 主引用文献: van Schooten, J.,Schorcht, A.,Farokhi, E.,Umotoy, J.C.,Gao, H.,van den Kerkhof, T.L.G.M.,Dorning, J.,Rijkhold Meesters, T.G.,van der Woude, P.,Burger, J.A.,Bijl, T.,Ghalaiyini, R.,Torrents de la Pena, A.,Turner, H.L.,Labranche, C.C.,Stanfield, R.L.,Sok, D.,Schuitemaker, H.,Montefiori, D.C.,Burton, D.R.,Ozorowski, G.,Seaman, M.S.,Wilson, I.A.,Sanders, R.W.,Ward, A.B.,van Gils, M.J.; Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer.; Plos Pathog., 18:e1010945-e1010945, 2022; PubMed: 36395347; DOI: 10.1371/journal.ppat.1010945

実験手法

ELECTRON MICROSCOPY (3.99 Å)