7ZL6
Azosemide in complex with human Carbonic anhydrase II (hCA II)
This is a non-PDB format compatible entry.
Summary for 7ZL6
Entry DOI | 10.2210/pdb7zl6/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, Azosemide, ... (4 entities in total) |
Functional Keywords | carbonic anhydrase, inhibitors, metalloenzyme, azosemide, loop diuteric, lyase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 29725.31 |
Authors | Angeli, A.,Ferraroni, M. (deposition date: 2022-04-14, release date: 2023-04-26, Last modification date: 2024-02-07) |
Primary citation | Ferraroni, M.,Angeli, A.,Pinteala, M.,Supuran, C.T. Sulfonamide diuretic azosemide as an efficient carbonic anhydrase inhibitor J.Mol.Struct., 1268:133672-, 2022 Cited by DOI: 10.1016/j.molstruc.2022.133672PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.383 Å) |
Structure validation
Download full validation report