7ZHA
Structure of human OCT3 in complex with inhibitor decynium-22
Summary for 7ZHA
Entry DOI | 10.2210/pdb7zha/pdb |
EMDB information | 14728 |
Descriptor | Solute carrier family 22 member 3, 1-ethyl-2-[(1-ethylquinolin-2-yl)methyl]quinoline (2 entities in total) |
Functional Keywords | organic cation transporter, major-facilitator superfamily, slc22 family, corticosterone sensitive protein, membrane transport, decynium-22, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 61661.29 |
Authors | Khanppnavar, B.,Korkhov, V. (deposition date: 2022-04-05, release date: 2022-11-09, Last modification date: 2023-04-19) |
Primary citation | Khanppnavar, B.,Maier, J.,Herborg, F.,Gradisch, R.,Lazzarin, E.,Luethi, D.,Yang, J.W.,Qi, C.,Holy, M.,Jantsch, K.,Kudlacek, O.,Schicker, K.,Werge, T.,Gether, U.,Stockner, T.,Korkhov, V.M.,Sitte, H.H. Structural basis of organic cation transporter-3 inhibition. Nat Commun, 13:6714-6714, 2022 Cited by PubMed: 36344565DOI: 10.1038/s41467-022-34284-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.55 Å) |
Structure validation
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