7ZHA

Structure of human OCT3 in complex with inhibitor decynium-22

7ZHA の概要

• エントリーDOI: 10.2210/pdb7zha/pdb
• EMDBエントリー: 14728
• 分子名称: Solute carrier family 22 member 3, 1-ethyl-2-[(1-ethylquinolin-2-yl)methyl]quinoline (2 entities in total)
• 機能のキーワード: organic cation transporter, major-facilitator superfamily, slc22 family, corticosterone sensitive protein, membrane transport, decynium-22, membrane protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61661.29

構造登録者

Khanppnavar, B.,Korkhov, V. (登録日: 2022-04-05, 公開日: 2022-11-09, 最終更新日: 2023-04-19)

• 主引用文献: Khanppnavar, B.,Maier, J.,Herborg, F.,Gradisch, R.,Lazzarin, E.,Luethi, D.,Yang, J.W.,Qi, C.,Holy, M.,Jantsch, K.,Kudlacek, O.,Schicker, K.,Werge, T.,Gether, U.,Stockner, T.,Korkhov, V.M.,Sitte, H.H.; Structural basis of organic cation transporter-3 inhibition.; Nat Commun, 13:6714-6714, 2022; PubMed: 36344565; DOI: 10.1038/s41467-022-34284-8

実験手法

ELECTRON MICROSCOPY (3.55 Å)