7ZH6

Structure of human OCT3 in complex with inhibitor Corticosterone

Summary for 7ZH6

Entry DOI	10.2210/pdb7zh6/pdb
EMDB information	14725
Descriptor	Solute carrier family 22 member 3, CORTICOSTERONE (2 entities in total)
Functional Keywords	organic cation transporter, major-facilitator superfamily, slc22 family, corticosterone-sensitive, membrane transport, steroid hormones, drug transporter, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	61679.30
Authors	Khanppnavar, B.,Korkhov, V. (deposition date: 2022-04-05, release date: 2022-11-09, Last modification date: 2023-04-19)
Primary citation	Khanppnavar, B.,Maier, J.,Herborg, F.,Gradisch, R.,Lazzarin, E.,Luethi, D.,Yang, J.W.,Qi, C.,Holy, M.,Jantsch, K.,Kudlacek, O.,Schicker, K.,Werge, T.,Gether, U.,Stockner, T.,Korkhov, V.M.,Sitte, H.H. Structural basis of organic cation transporter-3 inhibition. Nat Commun, 13:6714-6714, 2022 Cited by PubMed: 36344565 DOI: 10.1038/s41467-022-34284-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.67 Å)

Structure validation