7ZBG

Human Topoisomerase II Beta ATPase ADP

Summary for 7ZBG

Entry DOI	10.2210/pdb7zbg/pdb
Descriptor	DNA topoisomerase 2-beta, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ... (6 entities in total)
Functional Keywords	dna topoisomerase ii beta, human, atpase domain, top2b, dna binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	46785.72
Authors	Ling, E.M.,Basle, A.,Cowell, I.G.,Blower, T.R.,Austin, C.A. (deposition date: 2022-03-23, release date: 2022-05-25, Last modification date: 2024-01-31)
Primary citation	Ling, E.M.,Basle, A.,Cowell, I.G.,van den Berg, B.,Blower, T.R.,Austin, C.A. A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193. Structure, 30:1129-1145.e3, 2022 Cited by PubMed: 35660158 DOI: 10.1016/j.str.2022.05.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation