7Z9V

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 1,4-Anhydroerythritol

Summary for 7Z9V

• Entry DOI: 10.2210/pdb7z9v/pdb
• Descriptor: Cholinephosphate cytidylyltransferase, Guanidinium, (3~{S},4~{R})-oxolane-3,4-diol, ... (4 entities in total)
• Functional Keywords: plasmodium falciparum cct inhibitors fragments, transferase
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum)
• Total number of polymer chains: 1
• Total formula weight: 21198.57

Authors

Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2022-03-21, release date: 2023-03-29, Last modification date: 2024-02-07)

• Primary citation: Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R.; Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)