7Z9M
E.coli gyrase holocomplex with 217 bp DNA and Albi-1 (site AA)
Summary for 7Z9M
Entry DOI | 10.2210/pdb7z9m/pdb |
EMDB information | 14574 |
Descriptor | DNA gyrase subunit A, DNA gyrase subunit B, DNA (5'-D(P*AP*AP*AP*TP*CP*TP*GP*TP*GP*CP*GP*GP*GP*T)-3'), ... (9 entities in total) |
Functional Keywords | type ii topoisomerase, antibiotic, albicidin, dna gyrase, isomerase |
Biological source | Escherichia coli str. K-12 substr. MG1655 More |
Total number of polymer chains | 8 |
Total formula weight | 397968.29 |
Authors | Ghilarov, D.,Heddle, J.G.H. (deposition date: 2022-03-21, release date: 2023-02-15, Last modification date: 2023-07-19) |
Primary citation | Michalczyk, E.,Hommernick, K.,Behroz, I.,Kulike, M.,Pakosz-Stepien, Z.,Mazurek, L.,Seidel, M.,Kunert, M.,Santos, K.,von Moeller, H.,Loll, B.,Weston, J.B.,Mainz, A.,Heddle, J.G.,Sussmuth, R.D.,Ghilarov, D. Molecular mechanism of topoisomerase poisoning by the peptide antibiotic albicidin. Nat Catal, 6:52-67, 2023 Cited by PubMed: 36741192DOI: 10.1038/s41929-022-00904-1 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)