7Z70

Crystal structure of Angiotensin-1 converting enzyme C-domain in complex with fosinoprilat

7Z70 の概要

• エントリーDOI: 10.2210/pdb7z70/pdb
• 分子名称: Angiotensin-converting enzyme, CHLORIDE ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: angiotensin-1 converting enzyme, fosinoprilat, fosinopril, metalloprotease, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 71003.71

構造登録者

Cozier, G.E.,Acharya, K.R. (登録日: 2022-03-14, 公開日: 2022-06-22, 最終更新日: 2024-01-31)

• 主引用文献: Cozier, G.E.,Newby, E.C.,Schwager, S.L.U.,Isaac, R.E.,Sturrock, E.D.,Acharya, K.R.; Structural basis for the inhibition of human angiotensin-1 converting enzyme by fosinoprilat.; Febs J., 289:6659-6671, 2022; PubMed: 35653492; DOI: 10.1111/febs.16543

実験手法

X-RAY DIFFRACTION (1.85 Å)