7Z2K

Crystal structure of SARS-CoV-2 Main Protease in orthorhombic space group p212121

7Z2K の概要

• エントリーDOI: 10.2210/pdb7z2k/pdb
• 分子名称: 3C-like proteinase nsp5, MALONATE ION, SODIUM ION, ... (6 entities in total)
• 機能のキーワード: main protease, mpro, cystein protease, drug development, drug target, peptide-like inhibitor, sars-cov-2, covid-19, hydrolase
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 68183.48

構造登録者

Reinke, P.Y.A.,Falke, S.,Lieske, J.,Ewert, W.,Loboda, J.,Rahmani Mashhour, A.,Hauser, M.,Karnicar, K.,Usenik, A.,Lindic, N.,Lach, M.,Boehler, H.,Beck, T.,Cox, R.,Chapman, H.N.,Hinrichs, W.,Turk, D.,Guenther, S.,Meents, A. (登録日: 2022-02-28, 公開日: 2023-03-22, 最終更新日: 2024-02-07)

• 主引用文献: Reinke, P.Y.A.,Falke, S.,Lieske, J.,Ewert, W.,Loboda, J.,Rahmani Mashhour, A.,Hauser, M.,Karnicar, K.,Usenik, A.,Lindic, N.,Lach, M.,Boehler, H.,Beck, T.,Cox, R.,Chapman, H.N.,Hinrichs, W.,Turk, D.,Guenther, S.,Meents, A.; Sulfonated Calpeptin is a promising drug candidate against SARS-CoV-2 infections; To Be Published,

実験手法

X-RAY DIFFRACTION (1.65 Å)