7Z1F
Crystal structure of GSK3b in complex with CX-4945
Summary for 7Z1F
| Entry DOI | 10.2210/pdb7z1f/pdb |
| Descriptor | Glycogen synthase kinase-3 beta, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, IMIDAZOLE, ... (5 entities in total) |
| Functional Keywords | kinase, diabetes, kinase inhibitor, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 84293.54 |
| Authors | Grygier, P.,Pustelny, K.,Dubin, G.,Czarna, A. (deposition date: 2022-02-24, release date: 2023-03-08, Last modification date: 2024-11-20) |
| Primary citation | Grygier, P.,Pustelny, K.,Golik, P.,Popowicz, G.,Dubin, G.,Czarna, A. Crystal structure of phosphorylated (Tyr216) GSK3b kinase in complex with CX-4945 To Be Published, |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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