7Z12
VAR2 complex with PAM1.4
Summary for 7Z12
Entry DOI | 10.2210/pdb7z12/pdb |
EMDB information | 14438 |
Descriptor | PAM1.4, Heavy Chain, PAM1.4, light Chain, VAR2CSA (3 entities in total) |
Functional Keywords | var2csa, malaria, cell adhesion |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 312339.23 |
Authors | Raghavan, S.S.R.,Wang, K.T. (deposition date: 2022-02-24, release date: 2022-11-02, Last modification date: 2022-11-30) |
Primary citation | Raghavan, S.S.R.,Dagil, R.,Lopez-Perez, M.,Conrad, J.,Bassi, M.R.,Quintana, M.D.P.,Choudhary, S.,Gustavsson, T.,Wang, Y.,Gourdon, P.,Ofori, M.F.,Christensen, S.B.,Minja, D.T.R.,Schmiegelow, C.,Nielsen, M.A.,Barfod, L.,Hviid, L.,Salanti, A.,Lavstsen, T.,Wang, K. Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA. Plos Pathog., 18:e1010924-e1010924, 2022 Cited by PubMed: 36383559DOI: 10.1371/journal.ppat.1010924 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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