7YY2
Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Compound 20
Summary for 7YY2
Entry DOI | 10.2210/pdb7yy2/pdb |
Descriptor | Phosphopantetheine adenylyltransferase, 5-[3-(1~{H}-indol-3-yl)propoxy]-1-phenyl-pyrazole-4-carboxylic acid (3 entities in total) |
Functional Keywords | coad, ppat, nucleotidyltransferase, coenzyme a biosynthesis, transferase |
Biological source | Mycobacteroides abscessus |
Total number of polymer chains | 3 |
Total formula weight | 53514.84 |
Authors | Thomas, S.E.,Coyne, A.G.,Blundell, T.L. (deposition date: 2022-02-17, release date: 2022-06-29, Last modification date: 2024-01-31) |
Primary citation | Thomas, S.E.,McCarthy, W.J.,El Bakali, J.,Brown, K.P.,Kim, S.Y.,Blaszczyk, M.,Mendes, V.,Abell, C.,Floto, R.A.,Coyne, A.G.,Blundell, T.L. Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9:880432-880432, 2022 Cited by PubMed: 35712348DOI: 10.3389/fmolb.2022.880432 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.598 Å) |
Structure validation
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