7YXV

Crystal structure of a tautomerase superfamily member form Acinetobacter baumanii

7YXV の概要

• エントリーDOI: 10.2210/pdb7yxv/pdb
• 分子名称: Anthranilate synthase, NITRATE ION, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: cytosolic protein, tautomerase superfamily, 4-oxalocrotonate tautomerase, t6ss
• 由来する生物種: Acinetobacter baumannii
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15413.08

構造登録者

Pankov, G.,Hunter, W.N. (登録日: 2022-02-16, 公開日: 2022-05-18, 最終更新日: 2024-02-07)

主引用文献

Pankov, G.,Mol Avelar, G.,Buchanan, G.,Coulthurst, S.J.,Hunter, W.N.
The structure of a tautomerase superfamily member linked to the type VI secretion system of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 79:8-16, 2023

PubMed Abstract: Bacteria exploit specialized secretion systems to assist in competition for resources, in collaboration and in communication. Here, a protocol for the recombinant production, purification and crystallization of a protein linked to the Acinetobacter baumannii type VI secretion system is provided. A high-resolution structure of this trimeric protein is reported, revealing the characteristic dual β-α-β subunit fold typical of longer subunit members of the tautomerase superfamily. The protein does not appear to be toxic to bacteria or yeast under the conditions tested. The possible biological role of this protein is discussed.

PubMed: 36598351
DOI: 10.1107/S2053230X22011414

実験手法

X-RAY DIFFRACTION (1.7 Å)