7YW5

Crystal Structure of the ITS1 processing by human ribonuclease ISG20L2 with mutation D327A

Summary for 7YW5

• Entry DOI: 10.2210/pdb7yw5/pdb
• Descriptor: Interferon-stimulated 20 kDa exonuclease-like 2 (2 entities in total)
• Functional Keywords: ribonuclease, ribosomal protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 43568.19

Authors

Yang, X.Y.,Liu, X.H. (deposition date: 2022-08-21, release date: 2024-01-17, Last modification date: 2024-03-13)

• Primary citation: Ma, Y.,Wang, J.,He, X.,Liu, Y.,Zhen, S.,An, L.,Yang, Q.,Niu, F.,Wang, H.,An, B.,Tai, X.,Yan, Z.,Wu, C.,Yang, X.,Liu, X.; Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA.; Nucleic Acids Res., 52:1878-1895, 2024; PubMed: 38153123; DOI: 10.1093/nar/gkad1210

Experimental method

X-RAY DIFFRACTION (2.77 Å)