7YRQ

Cryo-EM structure of human Peroxisomal ABC Transporter ABCD1

Summary for 7YRQ

• Entry DOI: 10.2210/pdb7yrq/pdb
• EMDB information: 34064
• Descriptor: ATP-binding cassette sub-family D member 1, [(2~{R})-1-hexadecanoyloxy-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propan-2-yl] octadec-9-enoate (2 entities in total)
• Functional Keywords: structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 167603.90

Authors

Chao, X.,Li-Na, J.,Lin, T. (deposition date: 2022-08-10, release date: 2023-03-22, Last modification date: 2024-07-03)

• Primary citation: Xiong, C.,Jia, L.N.,Xiong, W.X.,Wu, X.T.,Xiong, L.L.,Wang, T.H.,Zhou, D.,Hong, Z.,Liu, Z.,Tang, L.; Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP.; Signal Transduct Target Ther, 8:74-74, 2023; PubMed: 36810450; DOI: 10.1038/s41392-022-01280-9

Experimental method

ELECTRON MICROSCOPY (3.35 Å)