7YOY

Cryo-EM structure of EBV gHgL-gp42 in complex with mAbs 3E8 and 5E3 (localized refinement)

7YOY の概要

• エントリーDOI: 10.2210/pdb7yoy/pdb
• EMDBエントリー: 33990
• 分子名称: Soluble gp42, 5E3 heavy chain, 3E8 heavy chain, ... (5 entities in total)
• 機能のキーワード: ebv, cryo-em, glycoprotein, ghgl-gp42 complex, antibody, viral protein
• 由来する生物種: Human gammaherpesvirus 4 (Epstein-Barr virus,HHV-4,Human herpesvirus 4); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 64248.65

構造登録者

Liu, L.,Sun, H.,Jiang, Y.,Hong, J.,Zheng, Q.,Li, S.,Chen, Y.,Xia, N. (登録日: 2022-08-02, 公開日: 2024-01-31)

• 主引用文献: Hong, J.,Zhong, L.,Liu, L.,Wu, Q.,Zhang, W.,Chen, K.,Wei, D.,Sun, H.,Zhou, X.,Zhang, X.,Kang, Y.F.,Huang, Y.,Chen, J.,Wang, G.,Zhou, Y.,Chen, Y.,Feng, Q.S.,Yu, H.,Li, S.,Zeng, M.S.,Zeng, Y.X.,Xu, M.,Zheng, Q.,Chen, Y.,Zhang, X.,Xia, N.; Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection.; Cell Rep Med, 4:101296-101296, 2023; PubMed: 37992686; DOI: 10.1016/j.xcrm.2023.101296

実験手法

ELECTRON MICROSCOPY (3.64 Å)