7YMV

Cryo-EM structure of MERS-CoV spike protein, Two RBD-up conformation 1

7YMV の概要

• エントリーDOI: 10.2210/pdb7ymv/pdb
• EMDBエントリー: 33943
• 分子名称: Spike glycoprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: mers-cov, spike, glycoprotein, viral protein
• 由来する生物種: Human betacoronavirus 2c EMC/2012
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 467388.67

構造登録者

Hsu, S.T.D.,Chang, N.E.,Weng, Z.W.,Yang, T.J.,Draczkowski, P. (登録日: 2022-07-29, 公開日: 2023-08-09, 最終更新日: 2024-09-04)

• 主引用文献: Tsai, Y.X.,Chang, N.E.,Reuter, K.,Chang, H.T.,Yang, T.J.,von Bulow, S.,Sehrawat, V.,Zerrouki, N.,Tuffery, M.,Gecht, M.,Grothaus, I.L.,Colombi Ciacchi, L.,Wang, Y.S.,Hsu, M.F.,Khoo, K.H.,Hummer, G.,Hsu, S.D.,Hanus, C.,Sikora, M.; Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.; Cell, 187:1296-1311.e26, 2024; PubMed: 38428397; DOI: 10.1016/j.cell.2024.01.034

実験手法

ELECTRON MICROSCOPY (6.74 Å)