7YK8

Cryo-EM structure of dLAG3-alpha-syn fibril

Summary for 7YK8

• Entry DOI: 10.2210/pdb7yk8/pdb
• EMDB information: 33890
• Descriptor: Alpha-synuclein (1 entity in total)
• Functional Keywords: protein fibril, amyloid
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 173713.30

Authors

Xu, Q.H.,Xia, W.C.,Tao, Y.Q.,Liu, C. (deposition date: 2022-07-22, release date: 2023-03-22, Last modification date: 2024-05-08)

• Primary citation: Zhang, S.,Li, J.,Xu, Q.,Xia, W.,Tao, Y.,Shi, C.,Li, D.,Xiang, S.,Liu, C.; Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.; J.Am.Chem.Soc., 145:4473-4484, 2023; PubMed: 36794997; DOI: 10.1021/jacs.2c10854

Experimental method

ELECTRON MICROSCOPY (2.8 Å)