7YJG

Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82C/L181M in complex with N-imidazolyl-pentanoyl-L-phenylalanine and hydroxylamine

7YJG の概要

• エントリーDOI: 10.2210/pdb7yjg/pdb
• 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, HYDROXYAMINE, ... (5 entities in total)
• 機能のキーワード: p450 bm3 heme domain, oxidoreductase
• 由来する生物種: Priestia megaterium NBRC 15308 = ATCC 14581
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 108993.93

構造登録者

Dong, S.,Chen, J.,Jiang, Y.,Cong, Z.,Feng, Y. (登録日: 2022-07-20, 公開日: 2023-05-24, 最終更新日: 2023-11-29)

• 主引用文献: Chen, J.,Dong, S.,Fang, W.,Jiang, Y.,Chen, Z.,Qin, X.,Wang, C.,Zhou, H.,Jin, L.,Feng, Y.,Wang, B.,Cong, Z.; Regiodivergent and Enantioselective Hydroxylation of C-H bonds by Synergistic Use of Protein Engineering and Exogenous Dual-Functional Small Molecules.; Angew.Chem.Int.Ed.Engl., 62:e202215088-e202215088, 2023; PubMed: 36417593; DOI: 10.1002/anie.202215088

実験手法

X-RAY DIFFRACTION (1.684 Å)