7YEP

2-APB bound state of mTRPV2

Summary for 7YEP

Entry DOI	10.2210/pdb7yep/pdb
EMDB information	33774
Descriptor	Transient receptor potential cation channel subfamily V member 2, 2-aminoethyl diphenylborinate (2 entities in total)
Functional Keywords	mtrpv2, 2-apb, structural protein, membrane protein
Biological source	Mus musculus (house mouse)
Total number of polymer chains	4
Total formula weight	345133.16
Authors	Su, N. (deposition date: 2022-07-06, release date: 2022-08-17, Last modification date: 2024-07-03)
Primary citation	Su, N.,Zhen, W.,Zhang, H.,Xu, L.,Jin, Y.,Chen, X.,Zhao, C.,Wang, Q.,Wang, X.,Li, S.,Wen, H.,Yang, W.,Guo, J.,Yang, F. Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands. Nat.Chem.Biol., 19:72-80, 2023 Cited by PubMed: 36163384 DOI: 10.1038/s41589-022-01139-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.83 Å)

Structure validation