7YAI

CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 3

Summary for 7YAI

• Entry DOI: 10.2210/pdb7yai/pdb
• EMDB information: 33713
• Descriptor: Calcium-transporting ATPase type 2C member 1, Nanobody head piece of megabody, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (4 entities in total)
• Functional Keywords: golgi ca2+/mn2+ transporter, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 118019.75

Authors

Chen, Z.,Watanabe, S.,Inaba, K. (deposition date: 2022-06-28, release date: 2023-03-22)

• Primary citation: Chen, Z.,Watanabe, S.,Hashida, H.,Inoue, M.,Daigaku, Y.,Kikkawa, M.,Inaba, K.; Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.; Sci Adv, 9:eadd9742-eadd9742, 2023; PubMed: 36867705; DOI: 10.1126/sciadv.add9742

Experimental method

ELECTRON MICROSCOPY (3.14 Å)