7Y90
Crystal Structure Analysis of cp1 bound BCL2
Summary for 7Y90
Entry DOI | 10.2210/pdb7y90/pdb |
Descriptor | Apoptosis regulator Bcl-2, cp1 peptide, (2R)-3-[2-(aminomethyl)-3-azanyl-1-[4-[2-(2-chloranylethanoylamino)ethylcarbamoyl]phenyl]prop-1-enyl]sulfanyl-2-(carboxyamino)propanoic acid, ... (4 entities in total) |
Functional Keywords | bcl2, cp1, complex, apoptosis |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 21277.11 |
Authors | Li, F.W. (deposition date: 2022-06-24, release date: 2023-11-15, Last modification date: 2024-02-28) |
Primary citation | Li, F.,Liu, J.,Liu, C.,Liu, Z.,Peng, X.,Huang, Y.,Chen, X.,Sun, X.,Wang, S.,Chen, W.,Xiong, D.,Diao, X.,Wang, S.,Zhuang, J.,Wu, C.,Wu, D. Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy. Nat Commun, 15:1476-1476, 2024 Cited by PubMed: 38368459DOI: 10.1038/s41467-024-45848-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)