7Y08

Crystal structure of Ricin A chain bound with (2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)glycyl-L-phenylalanine

Summary for 7Y08

Entry DOI	10.2210/pdb7y08/pdb
Related	7XZS
Descriptor	Ricin A chain, N-[(2-amino-4-oxo-1,4-dihydropteridin-7-yl)carbonyl]glycyl-L-phenylalanine, SULFATE ION, ... (4 entities in total)
Functional Keywords	hydrolase inhibitor, hydrolase
Biological source	Ricinus communis (castor bean)
Total number of polymer chains	1
Total formula weight	31500.31
Authors	Goto, M.,Higashi, S.,Ohba, T.,Kawata, R.,Nagatsu, K.,Suzuki, S.,Saito, R. (deposition date: 2022-06-03, release date: 2022-12-21, Last modification date: 2023-11-29)
Primary citation	Goto, M.,Higashi, S.,Ohba, T.,Kawata, R.,Nagatsu, K.,Suzuki, S.,Anslyn, E.V.,Saito, R. Conformational change in ricin toxin A-Chain: A critical factor for inhibitor binding to the secondary pocket. Biochem.Biophys.Res.Commun., 627:1-4, 2022 Cited by PubMed: 35998389 DOI: 10.1016/j.bbrc.2022.08.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation