7XVF

Nav1.7 mutant class2

Summary for 7XVF

• Entry DOI: 10.2210/pdb7xvf/pdb
• Related: 7XVE
• EMDB information: 33484 33485
• Descriptor: Sodium channel protein type 9 subunit alpha, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ... (11 entities in total)
• Functional Keywords: action potential, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 299523.14

Authors

Huang, G.,Wu, Q.,Li, Z.,Pan, X.,Yan, N. (deposition date: 2022-05-22, release date: 2022-08-10, Last modification date: 2023-03-01)

• Primary citation: Huang, G.,Wu, Q.,Li, Z.,Jin, X.,Huang, X.,Wu, T.,Pan, X.,Yan, N.; Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Na v 1.7.; Proc.Natl.Acad.Sci.USA, 119:e2209164119-e2209164119, 2022; PubMed: 35878056; DOI: 10.1073/pnas.2209164119

Experimental method

ELECTRON MICROSCOPY (2.8 Å)