7XV6

Crystal structure of the Human TR4 DNA-Binding Domain with C-terminal extension (DBD-CTE) Homodimer Bound to DR1 Response Element

7XV6 の概要

• エントリーDOI: 10.2210/pdb7xv6/pdb
• 分子名称: DNA (5'-D(*GP*GP*CP*AP*GP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*CP*TP*GP*C)-3'), NR2C2 protein, ... (5 entities in total)
• 機能のキーワード: transcriptional regulation, dna binding, protein-dna complex, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 30765.61

構造登録者

Liu, Y.,Chen, Z. (登録日: 2022-05-21, 公開日: 2022-12-28, 最終更新日: 2023-11-29)

• 主引用文献: Liu, Y.,Ma, L.,Li, M.,Tian, Z.,Yang, M.,Wu, X.,Wang, X.,Shang, G.,Xie, M.,Chen, Y.,Liu, X.,Jiang, L.,Wu, W.,Xu, C.,Xia, L.,Li, G.,Dai, S.,Chen, Z.; Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.; Nucleic Acids Res., 51:1443-1457, 2023; PubMed: 36651297; DOI: 10.1093/nar/gkac1259

実験手法

X-RAY DIFFRACTION (2.3 Å)